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In fact, most physiological increases in gene expression are only severalfold above endogenous levels <a href=http://buycialis.homes>viagra and cialis online</a> While this may seem counterintuitive given that MYRF and the secreted factors are co expressed in classical tumors, these authors demonstrated that MYRF binds directly to secreted factor loci and attenuates their expression, presumably avoiding ER stress that might accompany their overproduction
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